Highlights
• DMSO did not show acute toxicity on zebrafish embryos at the concentrations of 0.1%.
• Vanadium ions did not exhibit acute toxicity on zebrafish embryos at the concentration of 50 ppm.
• Synergistic acte toxicity was found in the simultaneous treatment of DMSO and vanadium.
• Developmental malformation in zebrafish embryos were observed with the synergistic effects.